Dithiothreitol EnhancesListeria monocytogenesMediated Cell Cytotoxicity
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چکیده
منابع مشابه
Cytotoxicity of monocrotaline in isolated rat hepatocytes: effects of dithiothreitol and fructose.
Monocrotaline (MCT) is a pyrrolizidine alkaloid present in plants of the Crotalaria species that causes cytotoxicity and genotoxicity, including hepatotoxicity in animals and humans. It is metabolized by cytochrome P-450 in the liver to the alkylating agent dehydromonocrotaline (DHM). In previous studies using isolated rat liver mitochondria, we observed that DHM, but not MCT, inhibited the act...
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ژورنال
عنوان ژورنال: Microbiology and Immunology
سال: 2000
ISSN: 0385-5600
DOI: 10.1111/j.1348-0421.2000.tb02517.x